{"id":2666,"date":"2009-04-23T15:14:22","date_gmt":"2009-04-23T18:14:22","guid":{"rendered":"http:\/\/antonini.med.br\/blog\/?p=2666"},"modified":"2022-02-15T03:29:21","modified_gmt":"2022-02-15T03:29:21","slug":"da-hmg-coa-ao-mevalonato-2","status":"publish","type":"post","link":"https:\/\/antonini.psc.br\/?p=2666","title":{"rendered":"Da HMG-CoA ao Mevalonato"},"content":{"rendered":"<p style=\"text-align: justify;\"><span class=\"content\"><!--more-->A <strong>3-HIDROXI-3-METILGLUTARILCOENZIMA A <\/strong>sofre uma rea\u00e7\u00e3o de redu\u00e7\u00e3o, catalisada pela HMG-CoA Redutase, que converte duas coenzimas <strong>NADPH + H+ <\/strong>em <strong>NADP+, <\/strong>liberando uma <strong>CoA-SH<\/strong> e convertendo-se em <strong>MEVALONATO<\/strong><\/span><\/p>\n<div style=\"text-align: center;\">[singlepic id=815 w=320 h=240 float=center]<\/div>\n<p style=\"text-align: justify;\"><span class=\"content\">O <strong>MEVALONATO <\/strong>sofre uma rea\u00e7\u00e3o de descarboxila\u00e7\u00e3o simult\u00e2nea \u00e0 uma rea\u00e7\u00e3o de desidrata\u00e7\u00e3o, formando a <a href=\"?p=2672\"><strong>UNIDADE ISOPREN\u00d3IDE<\/strong><\/a> <\/span><span class=\"content\"><br \/>\n<\/span><\/p>\n<p><span class=\"content\"> <\/span><\/p>\n<p><span class=\"content\">Copyright \u00a9 por Biblioteca Virtual Todos os direitos reservados.<\/span><\/p>\n<p><span class=\"content\"><span class=\"tiny\"><br \/>\n<\/span><\/span><\/p>\n<p style=\"text-align: center;\"><span class=\"content\">[ <a href=\"javascript:history.go(-1)\">Voltar<\/a> ]<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[80],"tags":[],"class_list":["post-2666","post","type-post","status-publish","format-standard","hentry","category-bioquimica"],"_links":{"self":[{"href":"https:\/\/antonini.psc.br\/index.php?rest_route=\/wp\/v2\/posts\/2666","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/antonini.psc.br\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/antonini.psc.br\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/antonini.psc.br\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/antonini.psc.br\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2666"}],"version-history":[{"count":1,"href":"https:\/\/antonini.psc.br\/index.php?rest_route=\/wp\/v2\/posts\/2666\/revisions"}],"predecessor-version":[{"id":29380,"href":"https:\/\/antonini.psc.br\/index.php?rest_route=\/wp\/v2\/posts\/2666\/revisions\/29380"}],"wp:attachment":[{"href":"https:\/\/antonini.psc.br\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2666"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/antonini.psc.br\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2666"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/antonini.psc.br\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2666"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}