{"id":4710,"date":"2009-06-19T14:29:53","date_gmt":"2009-06-19T17:29:53","guid":{"rendered":"http:\/\/antonini.med.br\/blog\/?p=4710"},"modified":"2022-02-15T03:28:43","modified_gmt":"2022-02-15T03:28:43","slug":"ganciclovir","status":"publish","type":"post","link":"https:\/\/antonini.psc.br\/?p=4710","title":{"rendered":"Ganciclovir"},"content":{"rendered":"<p><!--more--><\/p>\n<p style=\"text-align: justify;\">RECOMENDA\u00c7\u00c3O<\/p>\n<p style=\"text-align: justify;\">Reconstituir cada frasco-ampola com 10ml de \u00e1gua est\u00e9ril para inje\u00e7\u00e3o e diluir em volume adequado de soro apropriado, aplicando-se por infus\u00e3o endovenosa durante aproximadamente uma hora.<\/p>\n<p style=\"text-align: justify;\">INTRA-VENOSA EM &#8220;BOLO&#8221;<\/p>\n<p style=\"text-align: justify;\">N\u00e3o. A toxicidade pode aumentar.<\/p>\n<p style=\"text-align: justify;\">PERFUS\u00c3O INTERMITENTE<\/p>\n<p style=\"text-align: justify;\">Sim. Diluir o conte\u00fado reconstitu\u00eddo em soro e aplicar durante uma hora.<\/p>\n<p style=\"text-align: justify;\">INTRA-VENOSA CONT\u00cdNUA<\/p>\n<p style=\"text-align: justify;\">N\u00e3o recomendado, devido ao risco de contamina\u00e7\u00e3o por bact\u00e9rias.<\/p>\n<p style=\"text-align: justify;\">INTRAMUSCULAR<\/p>\n<p style=\"text-align: justify;\">Sim, mas pode causar irrita\u00e7\u00e3o no local da inje\u00e7\u00e3o devido ao pH elevado da solu\u00e7\u00e3o de inje\u00e7\u00e3o (pH @ 11). Tamb\u00e9m pode ser feito por via subcut\u00e2nea, mas com o mesmo risco de irrita\u00e7\u00e3o local.<\/p>\n<p style=\"text-align: justify;\">SOLU\u00c7\u00d5ES COMPAT\u00cdVEIS<\/p>\n<p style=\"text-align: justify;\">Soro fisiol\u00f3gico.<\/p>\n<p style=\"text-align: justify;\">Solu\u00e7\u00e3o de dextrose 5% em \u00e1gua.<\/p>\n<p style=\"text-align: justify;\">Solu\u00e7\u00e3o de Ringer.<\/p>\n<p style=\"text-align: justify;\">Solu\u00e7\u00e3o de Ringer-lactato.<\/p>\n<p style=\"text-align: justify;\">ESTABILIDADE<\/p>\n<p style=\"text-align: justify;\">Reconstitu\u00eddo no pr\u00f3prio frasco, 12 horas \u00e0 temperatura ambiente.<\/p>\n<p style=\"text-align: justify;\">Dilu\u00eddo, utilizar o mais r\u00e1pido poss\u00edvel devido ao risco de contamina\u00e7\u00e3o bacteriana. Caso n\u00e3o seja poss\u00edvel utilizar imediatamente, manter sob refrigera\u00e7\u00e3o por no m\u00e1ximo 24 horas, evitando o congelamento.<\/p>\n<p style=\"text-align: justify;\">OBSERVA\u00c7\u00d5ES<\/p>\n<p style=\"text-align: justify;\">N\u00e3o diluir com \u00e1gua bacteriost\u00e1tica. Utilizar somente \u00e1gua bi-destilada est\u00e9ril para inje\u00e7\u00e3o.<\/p>\n<p style=\"text-align: justify;\">Inspecionar o frasco ap\u00f3s a reconstitui\u00e7\u00e3o para evitar a presen\u00e7a de part\u00edculas e\/ou corpos estranhos.<\/p>\n<p style=\"text-align: justify;\">Fonte: F. Hoffmann &#8211; La Roche Ltd. Basil\u00e9ia &#8211; Su\u00ed\u00e7a.<\/p>\n<p style=\"text-align: center;\">[ <a href=\"javascript:history.go(-1)\">Voltar<\/a> ]<\/p>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[21,27],"tags":[],"class_list":["post-4710","post","type-post","status-publish","format-standard","hentry","category-h-p","category-noticias"],"_links":{"self":[{"href":"https:\/\/antonini.psc.br\/index.php?rest_route=\/wp\/v2\/posts\/4710","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/antonini.psc.br\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/antonini.psc.br\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/antonini.psc.br\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/antonini.psc.br\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=4710"}],"version-history":[{"count":1,"href":"https:\/\/antonini.psc.br\/index.php?rest_route=\/wp\/v2\/posts\/4710\/revisions"}],"predecessor-version":[{"id":26933,"href":"https:\/\/antonini.psc.br\/index.php?rest_route=\/wp\/v2\/posts\/4710\/revisions\/26933"}],"wp:attachment":[{"href":"https:\/\/antonini.psc.br\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=4710"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/antonini.psc.br\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=4710"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/antonini.psc.br\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=4710"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}